Noor A. Yusuf, Judith L. Green, Richard J. Wall, Ellen Knuepfer, Robert W. Moon, Christina Schulte-Huxel, Rebecca R. Stanway, Stephen R. Martin, Steven A. Howell, Christopher H. Douse, Ernesto Cota, Edward W. Tate, Rita Tewari, and Anthony A. Holder (2015). The Plasmodium class XIV myosin, MyoB, has a distinct subcellular location in invasive and motile stages of the malaria parasite and an unusual light chain. The Journal of Biological Chemistry 290(19): 12147-12164
Background: Malaria parasites possess two unusual class XIV myosins, myosin A that drives gliding motility and myosin B that is uncharacterized. Results: Myosin B is located at the extreme apical end of motile and invasive parasites, binding a very large and unusual light chain. Conclusion: Myosin B differs substantially from myosin A in location and function. Significance: An unusual myosin and its light chain extend the known diversity of these families.