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Activities of Autoimmune Unit

. Last Updated: 28 August 2014Hits: 10878

Services

The Autoimmune Unit specializes in the detection of autoantibodies, using immunofluorescence, enzyme linked immunosorbent assay(ELISA), immunoCAP and immunoblot techniques. Testing is available for most autoimmune diseases as listed below:

No.

Tests offered

Disease associated

Turn Around Time (Working days)

1

Extractable Nuclear Antigen (ENA) Screening

 Connective Tissue Disease

7

2

Extractable Nuclear Antigen (ENA) Specific antibodies

 

10

Anti-SSA/Ro

 Sjogren's Syndrome, Connective Tissue Diseases

Anti-SSB/La

 Sjogren's Syndrome

Anti-Sm

 Systemic Lupus Erythematosus (SLE)

Anti-U1RNP

 Mixed Connective Tissue Diseases

Anti-Jo-1

 Polydermatomyositis

Anti-Scl-70/Topoisomerase 1

 Systemic Sclerosis (Scleroderma)

Anti-centromere

 Limited Systemic Sclerosis (CREST)

3

Anti-Acetycholine Receptor antibodies

 Myasthenia Gravis

21

4

Anti-Smooth Muscle Ab

 Autoimmune Hepatitis

7

5

Anti-Parietal cells antibodies

 Pernicious Anaemia (Autoimmune Gastritis)

7

6

Anti-Mitochondrial antibodies

 Primary Billiary Cirrhosis

7

7

Anti-Neutrophil Cytoplasmic antibodies: P- and C- ANCA

 ANCA-associated Vasculitides Diseases

7

8

Anti-Liver-Kidney Microsome (LKM)

 Autoimmune Hepatitis

7

9

Anti-Cardiolipin Antibody : IgG & IgM

 Anti-Phospholipid Syndrome

10

10

Anti-Glomerular Basement Membrane

 Goodpasture's syndrome

10

11

Anti-Cyclic Citrullinated Protein (CCP)

 Rheumatoid Arthritis

14

12

Coeliac Antibodies:

Anti-Endomysium

 Coeliac Diseases

21

Anti-Gliadin

Anti- Tissue Transglutaminase

13

Anti-Aquaporin 4 (Anti-Aq4)

 Neuromyelitis Optica (NMO)

7

14

Anti-N-Methyl-D-Aspartate Receptor (NMDAR)

 Autoimmune Encephalopathies (Anti-NMDAR

 encephalitis)

7

15

Diabetes Mellitus Antibodies:

Anti-Glutamic Acid Decarboxylase

Anti Islet Cells

Anti-Insulinoma-Associated Antigen 2

Anti-Insulin

 Diabetes Mellitus Type 1

14

16

Paraneoplastic Neurological Syndrome (PNS) Antibodies: Anti-Ma, Anti-Yo, Anti-Ri, Anti-Hu, Anti-Amphiphysin, Anti-CV2

 Paraneoplastic Neurologic Syndrome (PNS)

14

17

Skin Antibodies for Pemphigoid disease:

Anti-BP 180 & Anti-BP230

 Pemphigoid Diseases

14

Anti-Desmoglein 1 & 3

 Pemphigus Diseases

18

Gangliosides antibodies: Anti-GM1, Anti-GM2, Anti-GM3, Anti-GD1a, Anti-GD1b, Anti-GT1b, Anti-GQ1b

 Multifocal motor neuropathy, Gullain-Barre

 syndrome

14

19

Anti-Voltage gated potassium channel (VGKC): Anti-LCI1, Anti-CASPR2

 Autoimmune Encephalopathies

7

20

 

 

 

 

 

 

 

 

Specific Liver antibodies:

Anti-AMA-M2

 Primary Billiary Cirrhosis

 

 

 

 

14

 

 

 

 

Anti- M2-3E/BPO

 Primary Billiary Cirrhosis

Anti- Sp100

 Primary Billiary Cirrhosis

Anti-PML

 Primary Billiary Cirrhosis

Anti-gp120

 Primary Billiary Cirrhosis

Anti-LKM1

 Autoimmune Hepatitis

Anti-LC-1

 Autoimmune Hepatitis

Anti-SLA/LP

 Autoimmune Hepatitis

Anti-Ro-52

 Autoimmune Hepatitis

21

Anti-Beta 2 glycoprotein IgM & IgG

 Anti-phospholipid syndrome

10

22

Anti-GABA-b receptors

 Autoimmune encephalitis

7

 

Frequently Asked Questions (FAQ)

 

Questions

Answers

1

What is the type of specimen required for the tests?

Blood or Serum

2

What is the type of specimen container/tube needed for sample collection?

Plain tube or serum gel tube

3

What is the volume of specimen required for the tests?

3-5ml for children; 5-10ml for adults.

4

Does the specimen need to be refrigerated/frozen during the transportation?

No.

5

Do I need to make an appointment for the test?

No. Specimen can be sent in anytime.

6

What is the charge for each test? (for non-government hospital)

Please refer IMR handbook for the charge for each test or contact our directory.

7

What kind of request form should be used for the tests?

IMR Request Form or Hospital Request Form.

8

Who should I contact for the results interpretation and clinical information?

Pathologist or medical officer available in Autoimmune Unit.

 

For enquiry, please contact: 03-26162781/2783

myGOV MAMPU JPA IKU MSC NMMR CRC MyHEALTH MOH Globinmed SPA krste.my

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