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Phytochemistry Unit

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RESEARCH

Research activities carried out in Phytochemistry

1. Method development in the separation and isolation of compounds from herbs and medicinal plants using HPLC, HPLC-Dioade Array Detection and GasChromatograph -Mass Selective Detector.
2. Identification of phytochemical markers in crude extracts, fractions and compounds from medicinal plants and herbs.
3. Isolation and structural elucidation of new metabolites from Malaysian Centella asiatica.
4. Bioassay Guided Fractionation of Phyllagathis rotundifolia (Tapak Sulaiman) for anti-oxidant activity.
5. Quantification and identification of polysaccharide contents in Hericium erinaceus (Monkey Head mushroom).
6. HPLC Method Development: Quantification of Goniothalamin in mice serum.
7. Phytochemical Analysis of the essential oils Curcuma xanthorriza.
8. Anti dust mites effect from Cymbopogan merdus and Azadisachata indica.

 

Activities

The Unit coordinates reception of samples for distribution to other units within HMRC and other Centres within IMR. In 2004, the number of staff in the Unit has increased from 5 to 8, 3 researchers and 5 support staff which has enhanced the strength of the Unit.

 

Extraction and Sample Preparation

The Unit processes plant samples collected and carried out various extraction procedures and sample preparation for other all units in HMRC and from other laboratories outside IMR through collaborative research.

 

Fractionation and Isolation of Compounds

Separation and isolation are carried out using various chromatography techniques such as preparative TLC, Flash Chromatography, column chromatography and preparative HPLC.