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Molecular Pathology Unit

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RESEARCH 

| 2005 | 2004 | 2003 | 2002 | 2001 | 2000 | 1999 | 1998 |

 

Year 2005

Molecular studies on disease biomarkers and pathogenesis of cancer: colorectal carcinoma as model ( Tan LP, Ng BK, Balraj P, Tan SK, Lim PKC )

Study of antineoplastic activity and cellular gene expression on nasopharyngeal carcinoma cell lines treated with microalgae extracts ( Lai PJ, Lim PKC, Ling SN, Chu WL, Mak JW )

Study of antineoplastic activity and cellular gene expression on nasopharyngeal carcinoma cell lines treated with microalgae extracts ( Lai PJ, Lim PKC, Ling SN, Chu WL, Mak JW )

Mutational Analysis of p53 and RB2/p130 Genes in Nasopharyngeal Carcinoma (NPC) ( Hoe LL, Sam CK )

PTEN mutational analysis in colorectal cancer tumours in Malaysia ( Balraj P, Siti R, Tan LP )

Year 2004

  Molecular studies on disease biomarkers and pathogenesis of cancer: colorectal carcinoma as a model ( Tan LP, Ng BK, Balraj P, Tan SK and Lim PKC )

  Study of Antineoplastic Activity and Cellular Gene Expression on Nasopharyngeal Carcinoma Cell Lines Treated with Microalgae Extracts ( Lai PJ, Lim PKC, Ling SN, Chu WL, Mak JW )

Year 2003

  Mutational analysis of the APC gene in Malaysian colorectal cancer patients (Balraj P, Lim PKC, Tan LP, Ng BK & Tan SK)

  Mechanism of action of antivirals against nasopharyngeal carcinoma at the molecular level (Lim PKC, Ling SN, Chu WL, Mak JW, Lai PJ, Tan BK & Ng BK)

Year 2002

  Mutational analysis of the APC gene (Balraj P, Lim PKC & Tan SK)

  Development of diagnostic test for Spinal Muscular Atrophy (SMA) (Balraj P, Siti Ruhana & Lim PKC)

Year 2001

  DNA vaccination of mice with Toxoplasma gondii P24 and mouse interleukin 12 genes (Lim PKC, Lee LN, Ng BK & Chong KH)

  B-cell epitope scanning of Toxocara canis recombinant fusion protein (Lim PKC & Ramlah M)

  Mutational analysis in-patients with tuberous sclerosis (Pauline B, Bock SY, Siti R & Harziah G)

  Analysis of xenobiotic enzyme gene polymorphisms associated with Hepatocellular Carcinoma (HCC) (Amyza S & Lim PKC)

Year 2000

  Cloning and expression of plasmepsin I from Plasmodium falciparum in yeast and bacterial systems (Lim PKC, Ng BK & Tan CS)

  Evaluation of different routes of DNA delivery using Toxoplasma gondii p 30 antigen as a model ( Lee LN , Lim PKC, Navaratnam V & Mak JW)

  Analysis of xenobiotic enzyme gene polymorphisms associated with Hepatocellular Carcinome (HCC) (Amyza MS, Navaratnam V, Lim PKC, Sharif MM & Lye MS)

  Anti-cancer screening of Eurycoma longifolia (Tongkat Ali) extracts using the MTT assay (Roslina H, Lim PKC, Tan SK & Chu TL)

  Establishment of Molecular Diagnostic Test for the Diagnosis of Angelman and Prader Willi Syndrome (Munirah A, Tan SK, Choy YS, Harziah G & Khoo ASB)

Year 1999

  Establishment of a mutation screening procedure for Factor IX gene mutations (Khoo ASB, Munirah A, Tan SK & Harziah G)

  The use of non-radioactive probe in molecular diagnostic testing of Prader-Willi/Angelman syndrome (Khoo ASB, Munirah A, Ee JN & Tan SK)

  Analysis of xenobiotic enzyme gene polymorphisms associated with Hepatocellular Carcinoma (HCC) (Amyza MS, Navaratnam V, Lim PKC, Sharif MM & Lye MS)

  Evaluation of DNA Vaccination for Toxoplasma gondii ( Lee LN , Lim PKC, Mak JW & Navaratnam V)

  Evaluation of three assay formats for the immunodiagnosis of human toxocariasis (Lim PKC, Yamasaki H et al )

  Establishment of the MTT assay for screening of potential anti-cancer agents (Roslina H, Lim PKC, Tan SK & Chu TL)

Year 1998

  Production and characterization of Plasmodium falciparum -specific monoclonal antibodies (Lim PKC, Radzan T & Amyza S)

  Development of a recombinant fusion protein based-dot blot assay for the immunodiagnosis of human toxocariasis (Lim PKC, Tan SK, Yamasaki H, Ngah Z, Hanisah S & Ramlah M)

  Development of recombinant Toxoplasma gondii antigens for diagnosis and vaccines (Lim PKC & Ng BK)

  Evaluation of DNA vaccination for Toxoplasma gondii (Khoo ASB, Lee LN & Lim PKC)

  Breast cancer study (Khoo ASB, Balraj P et al )

  Mutation analysis of the ornithine transcarbamylase (OTC) gene and prediction of the effects of the mutation by molecular modeling ((Khoo ASB, Balraj P, Rachedi A, Chin CN & Volpi L)

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