Objectives
The objectives of the CaRC are to: conduct research in cancers that are of local importance; improve assessment of prognosis of cancers by molecular characteristics analysis; provide better assessment of individual patient response to treatment; improve cure rate, quality of life and prevent occurrence of secondary malignancy; and study the aetiology and control of cancer through its surveillance, education, research and service activities.
Activities
Biomarkers for Diagnosis
Identification of new diagnostic markers , eg. colorectal cancer, leukaemia and head & neck cancers
Cancer Prevention
- Pre-symptomatic screening for patients at risk of developing colorectal cancer
- Pre-symptomatic screening for patients at risk of developing oral cancer
Cancer Intervention
- Screening for gene aberrations in Leukemia using molecular methods
- Develop strategies for early detection and evaluation of diagnostic modalities for head & neck cancers
Natural Product Discovery
- In vitro screening of microalgae extracts to identify new anti-proliferative/anti-viral compounds for nasopharyngeal carcinoma mechanism of action of potential compounds on cancer or viral genes
- In vitro screening of natural active compound for anti- proliferative properties from Hibiscus rosa sinensis
Biobanking
- Biobanking of various tissue from cancers of national interest (breast, colorectal, nasopharyngeal, etc.) for future research
Future Research
- Cancer biology: To study the mechanisms involved in tumour progression and metastasis
- Cancer intervention: Gene expression profiling for molecular classification / prognostication in acute leukaemia, breast cancer and head & neck cancers
- Cancer immunology: To study the role of biomolecules involved in cancer immunology to gain a better understanding of cancer development and progression for better management
