Introduction to Immunogenetics Unit

1

Class I HLA typing

2

Class II HLA typing

3

HLA B27, B5, B12, B1502, B5701

4

HLA crossmatching

5

HLA antibody detection - Specific antibody

6

HLA antibody detection - Screening Class I

7

HLA antibody detection - Screening Class II

1

Zailatul Hani Mohamad Yadzir, Rosmilah Misnan, Noormalin Abdullah, Masita Arip, Shahnaz Murad Identification of Major Allergens of Wildflower Honey. (2011) Southeast Asian Journal of Tropical Medicine and Public Health 42(2): 370-75

2

Choong-Chor Chang, Chun-Lai Too, Shahnaz Murad,

and Suraiya Hani Hussein

Association of HLA-B*1502 allele with carbamazepine induced toxic epidermal necrolysis and Stevens–Johnson syndrome in the multi-ethnic Malaysian population. 2011. International Journal of Dermatology, 50, 221–224

3

Too Chun-Lai, Leonid Padyukov, Jasbir Singh Dhaliwal, Emeli Lundstrom, Abqariyah Yahya, Nor Asiah Muhamad, Lars Klareskog, Lars Alfredsson, Per Tobias Larsson, Shahnaz Murad, for the Malaysian epidemiological Investigation of Rheumatoid Arthritis (MyEIRA) Study Group

Shared Epitope Alleles Remain A Risk Factor for Anti-Citrullinated Proteins Antibody (ACPA) –  Positive Rheumatoid Arthritis in Three Asian Ethnic Groups PLOS One June 2011 Volume 6  Issue 6 e21069

4

JS Dhaliwal, M Shahnaz, A Azrena, Irda YA, Salawati M, CL Too, and Lee YY Gene frequencies of HLA-A, -B and –DR alleles in 3 indigenous populations of Sabah and Sarawak. Tissue Antigens 75:166-169(2011)

5

Adiratna Mat Ripen1,2, Takeshi Nitta1, Shigeo Murata3, Keiji Tanaka4, Yousuke Takahama1,*Ontogeny of thymic cortical epithelial cells expressing the thymoproteasome subunit β5t. European Journal of Immunology 411, 278–1287, May 2011

6

JS Dhaliwal, Lily Wong, Muhammad Amir Kamaluddin, Lee Yin Yin and Shahnaz Murad.  Susceptibility to Aplastic Anaemia is associated with HLA-DRB1*1501 in an aboriginal population in Sabah, Malaysia. Human Immunology (in press) 2011

7

Uma Devi Palanisamy, Muniswaran Sivanathan, Ammu Kutty Radhakrishnan, Nagaraja Haleagrahara, Thavamanithevi Subramaniam and Gan Seng Chiew. An Effective Ostrich Oil Bleaching Technique Using Peroxide Value as an Indicator. Molecules 2011, 16, 5709-5719

1.

Identification of the Major Allergens of Macrobrachium rosenbergii (Giant Freshwater Prawn) by Two-Dimensional Electrophoresis and Mass Spectrometry

Zailatul Hani Mohamad Yadzir

11-13th March 2011, 12th Malaysian Congress and Exhibition on Allergy and Immunogy, Sheraton Imperial Kuala Lumpur

2.

Detection of autoantibodies (anti-gliadin, anti-tissue transglutaminase and anti-endomysium) in diagnosis of celiac disease- A preliminary report.

Dr Ainur Yusniza Yusof

11-13th March 2011, 12th Malaysian Congress and Exhibition on Allergy and Immunogy, Sheraton Imperial Kuala Lumpur

3.

Detection of Antiphospholipid Antibodies In Female With Fetal Loss

Ching Yee Ming

11-13th March 2011,

12th Malaysian Congress and Exhibition on Allergy and Immunogy, Sheraton Imperial Kuala Lumpur

4.

High Resolution DNA Typing of HLA-A, -B & -DRB1 Loci by PCR-SSOP-Luminex in Malay Population

Norfarhana Khairul Fahmy

11-13th March 2011,

12th Malaysian Congress and Exhibition on Allergy and Immunogy, Sheraton Imperial Kuala Lumpur

5.

Detection of Neuronal Autoantibodies (Anti-Hu, Anti-Ri, Anti-Yo, Anti-Ma  and Anti-Amphiphysin) in patients with Paraneoplastic Neurological Syndrome (PNS)

Dr Masita Arip

11-13th March 2011,

12th Malaysian Congress and Exhibition on Allergy and Immunogy, Sheraton Imperial Kuala Lumpur

6.

Allergy to Paracetamol: Two Cases of Successful Rapid Desensitization with Paracetamol

Dr. Noormalin Abdullah

11-13th March 2011,

12th Malaysian Congress and Exhibition on Allergy and Immunogy, Sheraton Imperial Kuala Lumpur

7

A Retrospective Study of Frequency of Autoantibodies (Anti -Islet Cells (ICA), Anti-Glutamic Acid Decarboxylase (GAD), Insulin Autoantibodies (IAA) and Anti-Tyrosine Phosphatase (IA2) ) In Type 1 Diabetes 

Dr Norhazlin Mustafa

11-13th March 2011,

12th Malaysian Congress and Exhibition on Allergy and Immunogy, Sheraton Imperial Kuala Lumpur

8

Defining B cell defects in Primary Immunodeficiency patients in Malaysia (Tajuk pembentangan lisan: Analysis of Bruton’s Tyrosine Kinase (BTK) expression in Monocytes by Flow Cytometry)

Chear Chai Teng

11-13th March 2011,

12th Malaysian Congress and Exhibition on Allergy and Immunogy, Sheraton Imperial Kuala Lumpur

9

Wiskott-Aldrich protein expression in a child with X linked thrombocytopenia

Dr Gill HK

11-13th March 2011,

12th Malaysian Congress and Exhibition on Allergy and Immunogy, Sheraton Imperial Kuala Lumpur

10

“Identification Of Bruton’s Tyrosine Kinase Gene (Btk) Mutation In A Malaysian Family with X-Linked Agammaglobulinemia”

Chear CT

9 - 10 June 2011, Armada Hotel, Petaling Jaya Rare Disorder & Genetics Conference 2011

11

Evaluation of Saliva As A Source of DNA for Human Leukocyte Antigen (HLA) – A Pilot Study

Dr Masita Arip

18 – 19 June 2011, Meritus Pelangi Beach Resort, Langkawi

10th Annual Scientific Meeting, College of Pathologists AMM

12

Distribution of HLA-A, -B & -DRB1 Alleles Among the Malay Population in Malaysian Marrow Donor Registry (MMDR)

Norfarhana Khairul Fahmy

18 – 19 June 2011, Meritus Pelangi Beach Resort, Langkawi

10th Annual Scientific Meeting, College of Pathologists AMM

13

HLA-A, -B & -DR Alleles Frequencies in Chinese Population: A Malaysian Marrow Donor Registry Experience

Dr Norhazlin Mustafa

18 – 19 June 2011, Meritus Pelangi Beach Resort, Langkawi

10th Annual Scientific Meeting, College of Pathologists AMM

14

HLA-A, -B and –DR Alleles and frequencies among Indians in Malaysian Marrow Donor Registry

Salawati Mansor

18 – 19 June 2011, Meritus Pelangi Beach Resort, Langkawi

10th Annual Scientific Meeting, College of Pathologists AMM